West Ham welcome Sevilla, as Barcelona and Atalanta take on Galatasary and Leverkusen respectively.
After the playoffs rounds, on Thursday, the fight for the trophy got more exciting as the likes of fans favorites, BVB Dortmund, Napoli and Lazio were knocked out, while Braga, Betis and Sevilla advanced to the next stage.
The round of 16 takes place on the 10th of March and return leg on 17th March.
The pairings for the round are;
Rangers vs Red Star Belgrade
Braga vs Monaco
FC Porto vs Lyon
Atalanta vs Bayer Leverkusen
Sevilla vs West Ham
Barcelona vs Galatasaray
RB Leipzig vs Spartak Moscow
Real Betis vs Eintracht Frankfurt
UEFA Europa League dates
March 10 & 17: Round of 16
March 18 Quarter-final & Semi-final draw
April 7 &14: Quarter-finals
April 18 and May 5: Semi-finals
May 18: Final (Seville, Spain)
All dates are provisional and subject to change by UEFA